873061-79-1

873061-79-1 structure

Name: Ganoderone A
Chemical Name: Ganoderone A
CAS Number: 873061-79-1
Molecular Formula: C₃₀H₄₆O₃
Molecular Weight: 454.684
Catalog: Signaling Pathways Anti-infection HSV
Create Date: 2018-10-16 08:46:14
Modify Date: 2024-01-07 21:30:47
Ganoderone A is a triterpene compound that can be isolated from the fruiting body of Ganoderma pfeifferi and Ganoderma calidophilum. Ganoderone A has antiviral activity against HSV with IC50 value of 0.3 µg/mL. Ganoderone A has potential applications in viral infections and tumors[1][2][3].

Name	Ganoderone A
Synonyms	Lanosta-8,24-diene-3,7-dione, 26-hydroxy-, (24E)- (24E)-26-Hydroxylanosta-8,24-diene-3,7-dione GANODERONE A

Description	Ganoderone A is a triterpene compound that can be isolated from the fruiting body of Ganoderma pfeifferi and Ganoderma calidophilum. Ganoderone A has antiviral activity against HSV with IC50 value of 0.3 µg/mL. Ganoderone A has potential applications in viral infections and tumors[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection
Target	HSV:0.3 μg/mL (IC50)
In Vitro	Ganoderone A 对 K562、BEL7402 和 SGC790 细胞系展现出细胞毒性活性，IC50 值分别为 7.62 µM、6.28 µM 和 3.55 µM[3]。
References	[1]. Niedermeyer TH, et al. Antiviral Terpenoid Constituents of Ganoderma pfeifferi. J Nat Prod. 2005 Dec;68(12):1728-31. [2]. Huang S Z, et al. Anti-allergic prenylated hydroquinones and alkaloids from the fruiting body of Ganoderma calidophilum[J]. RSC advances, 2016, 6(25): 21139-21147. [3]. Huang SZ, et al. Lanostane-type triterpenoids from the fruiting body of Ganoderma calidophilum. Phytochemistry. 2017 Nov;143:104-110.