1180504-64-6

1180504-64-6 structure

Name: (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane
Chemical Name: 7-Hydroxy-3-(4-hydroxybenzyl)chroman
CAS Number: 1180504-64-6
Molecular Formula: C₁₆H₁₆O₃
Molecular Weight: 256.29644
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2018-06-02 22:31:37
Modify Date: 2024-01-10 11:28:03
(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane is a homoisoflavonoid. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane increases the level of alkaline phosphatase (ALP) activity. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane promotes mesenchymal stem cells (MSCs) osteogenesis, but cannot enhance MSCs proliferation. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane can be used for osteoporosis research[1].

Name	7-Hydroxy-3-(4-hydroxybenzyl)chroman

Description	(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane is a homoisoflavonoid. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane increases the level of alkaline phosphatase (ALP) activity. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane promotes mesenchymal stem cells (MSCs) osteogenesis, but cannot enhance MSCs proliferation. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane can be used for osteoporosis research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Metabolic Disease
Target	Alkaline phosphatase (ALP)[1]
In Vitro	(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane (10 μM) 通过增加碱性磷酸酶 (ALP) 活性水平显著促进 MSCs 成骨分化。与对照组相比，早期成骨细胞分化率为162.0±1.4[1]。
References	[1]. Xu X, et al. Isolation and chatacterization of homoisoflavonoids from Dracaena cochinchinensis and their osteogenic activities in mouse mesenchymal stem cells. J Pharm Biomed Anal. 2016 Sep 10;129:466-472.

Molecular Formula	C₁₆H₁₆O₃
Molecular Weight	256.29644