(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane

Modify Date: 2024-01-10 11:28:03

(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane Structure
(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane structure
Common Name (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane
CAS Number 1180504-64-6 Molecular Weight 256.29644
Density N/A Boiling Point N/A
Molecular Formula C16H16O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane


(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane is a homoisoflavonoid. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane increases the level of alkaline phosphatase (ALP) activity. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane promotes mesenchymal stem cells (MSCs) osteogenesis, but cannot enhance MSCs proliferation. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane can be used for osteoporosis research[1].

 Names

Name 7-Hydroxy-3-(4-hydroxybenzyl)chroman

  Biological Activity

Description (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane is a homoisoflavonoid. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane increases the level of alkaline phosphatase (ALP) activity. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane promotes mesenchymal stem cells (MSCs) osteogenesis, but cannot enhance MSCs proliferation. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane can be used for osteoporosis research[1].
Related Catalog
Target

Alkaline phosphatase (ALP)[1]

In Vitro (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane (10 μM) 通过增加碱性磷酸酶 (ALP) 活性水平显著促进 MSCs 成骨分化。与对照组相比,早期成骨细胞分化率为162.0±1.4[1]。
References

[1]. Xu X, et al. Isolation and chatacterization of homoisoflavonoids from Dracaena cochinchinensis and their osteogenic activities in mouse mesenchymal stem cells. J Pharm Biomed Anal. 2016 Sep 10;129:466-472.  

 Chemical & Physical Properties

Molecular Formula C16H16O3
Molecular Weight 256.29644