1310827-27-0

1310827-27-0 structure

Name: Azido-PEG3-SS-PEG3-azide
Chemical Name: Azido-PEG3-SS-PEG3-azide
CAS Number: 1310827-27-0
Molecular Formula: C₁₆H₃₂N₆O₆S₂
Molecular Weight: 468.592
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-23 05:30:47
Modify Date: 2024-01-08 23:23:20
Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG3-SS-PEG3-azide
Synonyms	MFCD28976667 3,6,9,16,19,22-Hexaoxa-12,13-dithiatetracosane, 1,24-diazido- 1,24-Diazido-3,6,9,16,19,22-hexaoxa-12,13-dithiatetracosane

Description	Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562