1807534-77-5

1807534-77-5 structure

Name: Fluorescein-PEG3-NH-Boc
Chemical Name: Fluorescein-PEG3-(N-Boc)-Amine
CAS Number: 1807534-77-5
Molecular Formula: C₃₄H₃₉N₃O₁₀S
Molecular Weight: 681.753
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-16 15:08:00
Modify Date: 2024-01-08 08:52:05
Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Fluorescein-PEG3-(N-Boc)-Amine
Synonyms	5-{[(2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)carbamothioyl]amino}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid MFCD23726634 Benzoic acid, 5-[(17,17-dimethyl-15-oxo-1-thioxo-5,8,11,16-tetraoxa-2,14-diazaoctadec-1-yl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-

Description	Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562