52436-42-7
52436-42-7 structure
- Name: Propargyl-PEG1-acrylate
- Chemical Name: Propargyl-PEG2- acrylate
- CAS Number: 52436-42-7
- Molecular Formula: C8H10O3
- Molecular Weight: 154.163
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-10 19:45:42
- Modify Date: 2024-01-09 18:57:20
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Propargyl-PEG1-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Propargyl-PEG2- acrylate |
|---|---|
| Synonyms | PROPARGYL-PEG2-AC |
| Description | Propargyl-PEG1-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 214.9±15.0 °C at 760 mmHg |
| Molecular Formula | C8H10O3 |
| Molecular Weight | 154.163 |
| Flash Point | 81.7±15.0 °C |
| Exact Mass | 154.062988 |
| LogP | 1.04 |
| Vapour Pressure | 0.2±0.4 mmHg at 25°C |
| Index of Refraction | 1.451 |