65247-27-0

65247-27-0 structure

Name: Cucurbitacin B 2-O-beta-D-glucoside
Chemical Name: arvenin I
CAS Number: 65247-27-0
Molecular Formula: C₃₈H₅₆O₁₃
Molecular Weight: 720.843
Catalog: Research Areas Cancer
Create Date: 2018-10-17 16:13:19
Modify Date: 2024-01-03 20:02:59
Arvenin I is a natural cucurbitacin glucoside with moderate anticancer effects[1].

Name	arvenin I
Synonyms	(2S,4R,9β,16α,23E)-2-(β-D-Glucopyranosyloxy)-16,20-dihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate Estr-5-ene-3,11-dione, 17-[(1R,3E)-5-(acetyloxy)-1-hydroxy-1,5-dimethyl-2-oxo-3-hexen-1-yl]-2-(β-D-glucopyranosyloxy)-16-hydroxy-4,4,9,14-tetramethyl-, (2β,9β,10α,16α,17β)-

Description	Arvenin I is a natural cucurbitacin glucoside with moderate anticancer effects[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Arvenin I 在 A-549、HT-29、OVCAR 和 MCF-7 癌细胞系中表现出中等活性，IC50 值分别为 17.0 µM、49.4 µM、14.7 µM 和 42.8 µM[1]。
References	[1]. Chau Van Minh, et al. Chemical constituents of Trichosanthes kirilowii and their cytotoxic activities. Arch Pharm Res. 2015 Aug;38(8):1443-8.