810677-16-8
810677-16-8 structure
- Name: Mal-PEG1-Boc
- Chemical Name: Mal-PEG1-t-butyl ester
- CAS Number: 810677-16-8
- Molecular Formula: C13H19NO5
- Molecular Weight: 269.294
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-11 09:01:23
- Modify Date: 2024-02-01 12:13:09
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Mal-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Mal-PEG1-t-butyl ester |
|---|---|
| Synonyms |
MFCD28142478
2-Methyl-2-propanyl 3-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]propanoate Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 1,1-dimethylethyl ester |
| Description | Mal-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 390.5±22.0 °C at 760 mmHg |
| Molecular Formula | C13H19NO5 |
| Molecular Weight | 269.294 |
| Flash Point | 190.0±22.3 °C |
| Exact Mass | 269.126312 |
| LogP | 1.32 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.498 |