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2138299-33-7

2138299-33-7 structure
2138299-33-7 structure
  • Name: STING agonist compound 3
  • Chemical Name: diABZI STING agonist-1
  • CAS Number: 2138299-33-7
  • Molecular Formula: C42H51N13O7
  • Molecular Weight: 849.94
  • Catalog: Signaling Pathways Immunology/Inflammation STING
  • Create Date: 2019-02-09 22:14:46
  • Modify Date: 2024-01-14 20:01:17
  • diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist.

Name diABZI STING agonist-1
Description diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist.
Related Catalog
Target

STING[1].

In Vivo diABZI STING agonist-1 activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting−/− mice, confirming that diABZI STING agonist-1 induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].
References

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

Molecular Formula C42H51N13O7
Molecular Weight 849.94