Shanghai Nianxing Industrial Co., Ltd
China
Product Name: c-Fms-IN-8
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Purity: 99.0%
Stocking Period: 10 Day
Contact: Huang

1255303-58-2

1255303-58-2 structure

1255303-58-2 structure

Name: c-Fms-IN-8
Chemical Name: c-Fms-IN-8
CAS Number: 1255303-58-2
Molecular Formula: C₂₇H₃₀N₂O₅
Molecular Weight: 462.54
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK c-Fms
Create Date: 2019-06-30 09:04:15
Modify Date: 2024-01-09 15:10:06
c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].

Name	c-Fms-IN-8

Description	c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms
Target	IC50: 9.1 nM (CSF-1R)[1].
References	[1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.

Molecular Formula	C₂₇H₃₀N₂O₅
Molecular Weight	462.54