1628574-50-4

1628574-50-4 structure

Name: c-Fms-IN-9
Chemical Name: c-Fms-IN-9
CAS Number: 1628574-50-4
Molecular Formula: C₂₁H₂₃N₇O₂
Molecular Weight: 405.45
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK c-Fms
Create Date: 2019-06-30 10:13:15
Modify Date: 2024-01-13 23:13:00
c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

Name	c-Fms-IN-9

Description	c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms
Target	c-FMS[1]
In Vitro	c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC50s of 0.01-0.1 μM[1].
References	[1]. Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.

Molecular Formula	C₂₁H₂₃N₇O₂
Molecular Weight	405.45