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  • DC Chemicals Limited
  • China
  • Product Name: FD-IN-1
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1646682-14-5

1646682-14-5 structure
1646682-14-5 structure
  • Name: FD-IN-1
  • Chemical Name: FD-IN-1
  • CAS Number: 1646682-14-5
  • Molecular Formula: C23H23NO4
  • Molecular Weight: 377.43
  • Catalog: Signaling Pathways Immunology/Inflammation Complement System
  • Create Date: 2019-06-30 20:40:15
  • Modify Date: 2024-01-10 07:47:12
  • FD-IN-1 (Compound 12) is a factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively[1].

Name FD-IN-1
Description FD-IN-1 (Compound 12) is a factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively[1].
Related Catalog
References

[1]. Karki RG, et al. Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway. J Med Chem. 2019 May 9;62(9):4656-4668.

Molecular Formula C23H23NO4
Molecular Weight 377.43