2301916-69-6

2301916-69-6 structure

Name: PROTAC FAK degrader 1
Chemical Name: PROTAC FAK degrader 1
CAS Number: 2301916-69-6
Molecular Formula: C₄₇H₅₆F₃N₉O₈S₂
Molecular Weight: 996.13
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FAK
Create Date: 2019-06-29 14:51:05
Modify Date: 2024-01-03 07:19:29
PROTAC FAK degrader 1 is a selective and potent focal adhesion kinase (Fak) degrader with an IC50 of 6.5 nM, DC50 of 3 nM[1].

Name	PROTAC FAK degrader 1

Description	PROTAC FAK degrader 1 is a selective and potent focal adhesion kinase (Fak) degrader with an IC50 of 6.5 nM, DC50 of 3 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FAK
Target	IC50: 6.5 nM (Focal adhesion kinase) DC50: 3 nM (Focal adhesion kinase)[1]
References	[1]. Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.