2042211-13-0

2042211-13-0 structure
2042211-13-0 structure
  • Name: Mcl1-IN-11
  • Chemical Name: Mcl1-IN-11
  • CAS Number: 2042211-13-0
  • Molecular Formula: C38H41N3O5S2
  • Molecular Weight: 683.88
  • Catalog: Signaling Pathways Apoptosis Bcl-2 Family
  • Create Date: 2019-08-04 15:06:59
  • Modify Date: 2024-01-13 16:46:24
  • Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1].

Name Mcl1-IN-11
Description Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1].
Related Catalog
Target

Ki: 0.06 (Mcl-1), 4.2 μM (Bcl-2)[1]

References

[1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.

Molecular Formula C38H41N3O5S2
Molecular Weight 683.88