Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Mcl1-IN-12
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Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

2042211-12-9

2042211-12-9 structure

2042211-12-9 structure

Name: Mcl1-IN-12
Chemical Name: Mcl1-IN-12
CAS Number: 2042211-12-9
Molecular Formula: C₄₅H₄₆N₄O₆S₂
Molecular Weight: 803.00
Catalog: Signaling Pathways Apoptosis Bcl-2 Family
Create Date: 2019-08-03 17:48:59
Modify Date: 2024-01-02 16:21:05
Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity[1].

Name	Mcl1-IN-12

Description	Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
Target	Ki: 0.29 (Mcl-1), 3.1 μM (Bcl-2)[1]
References	[1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.

Molecular Formula	C₄₅H₄₆N₄O₆S₂
Molecular Weight	803.00