189808-70-6

189808-70-6 structure

Name: Amino-PEG3-CH2CO2-t-butyl ester
Chemical Name: PROTAC Linker 5
CAS Number: 189808-70-6
Molecular Formula: C₁₂H₂₅NO₅
Molecular Weight: 263.33
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-08-03 18:54:58
Modify Date: 2024-01-09 16:24:16
PROTAC Linker 5 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	PROTAC Linker 5
Synonyms	MFCD30730374

Description	PROTAC Linker 5 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₂H₂₅NO₅
Molecular Weight	263.33

Hazard Codes	Xi