- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: NH2-PEG3-C2-Boc
- Price:
- Purity: 80.0%
- Stocking Period: 10 Day
- Contact: Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: NH2-PEG3-C2-Boc
- Price: ￥2140.0/1g ￥8620.0/5g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: Propanoic acid,3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- Price: ￥Inquiry/10g
- Purity: 95.0%
- Stocking Period: Inquiry
- Contact: Lihua Yang
- DC Chemicals Limited
- China
- Product Name: Amino-PEG3-t-butyl ester
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
252881-74-6
252881-74-6 structure
- Name: NH2-PEG3-C2-Boc
- Chemical Name: tert-butyl 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoate
- CAS Number: 252881-74-6
- Molecular Formula: C13H27NO5
- Molecular Weight: 277.35700
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-10-15 10:35:21
- Modify Date: 2024-01-04 20:29:14
-
NH2-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | tert-butyl 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoate |
|---|---|
| Synonyms |
H2N-OEG-CO2tBu
tert-butyl 3-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}propanoate tert-Butyl 3-[2-(2-(2-aminoethoxy)ethoxy)ethoxy]propionate NH2(CH2CH2O)3CH2CH2COOt-Bu 12-amino-4,7,10-trioxadodecanoic acid tert-butyl ester Amin PEG3-t-butyl ester tert-butyl 12-amino-4,7,10-trioxododecanoate tert-Butyl 12-amino-4,7,10-trioxadodecanoate 3-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]propionic acid tert-butyl ester |
| Description | NH2-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
| References |
| Molecular Formula | C13H27NO5 |
|---|---|
| Molecular Weight | 277.35700 |
| Flash Point | 169.7ºC |
| Exact Mass | 277.18900 |
| PSA | 80.01000 |
| LogP | 1.42700 |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| HS Code | 2922509090 |
|
~%
252881-74-6 |
| Literature: US2006/205670 A1, ; Page/Page column 105 ; |
| Precursor 1 | |
|---|---|
| DownStream 1 | |
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |