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838842-80-1

838842-80-1 structure
838842-80-1 structure
  • Name: LDN-76070
  • Chemical Name: LDN-76070
  • CAS Number: 838842-80-1
  • Molecular Formula: C18H17BrFNO4
  • Molecular Weight: 410.239
  • Create Date: 2020-01-11 18:11:51
  • Modify Date: 2024-09-08 17:14:09
  • LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice (5 mg/kg).

Name LDN-76070
Description LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice (5 mg/kg).
References References 1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610. 2. Cherry JJ, et al. EMBO Mol Med. 2013 Jul;5(7):1103-18. View Related Products by Target SMN2 Modulator
Molecular Formula C18H17BrFNO4
Molecular Weight 410.239