1177148-36-5
1177148-36-5 structure
- Name: ML 086 (CID-1674999)
- Chemical Name: ML 086
- CAS Number: 1177148-36-5
- Molecular Formula: C16H14N2O2S
- Molecular Weight: 298.36
- Create Date: 2020-01-11 21:43:50
- Modify Date: 2023-01-15 16:05:35
-
ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM); a useful chemical tool to examine the functional role of this enzyme in skeletal mineralization and soft tissue ossification abnormalities.
| Name | ML 086 |
|---|
| Description | ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM); a useful chemical tool to examine the functional role of this enzyme in skeletal mineralization and soft tissue ossification abnormalities. |
|---|---|
| References | References 1. Stonich D, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. 2. Bravo Y, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4308-11. View Related Products by Target Protein Phosphatase/PTP |
| Molecular Formula | C16H14N2O2S |
|---|---|
| Molecular Weight | 298.36 |