ML 086 (CID-1674999)

Modify Date: 2024-08-11 13:31:24

ML 086 (CID-1674999) Structure
ML 086 (CID-1674999) structure
Common Name ML 086 (CID-1674999)
CAS Number 1177148-36-5 Molecular Weight 298.36
Density N/A Boiling Point N/A
Molecular Formula C16H14N2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ML 086 (CID-1674999)


ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM); a useful chemical tool to examine the functional role of this enzyme in skeletal mineralization and soft tissue ossification abnormalities.

 Names

Name ML 086

 ML 086 (CID-1674999) Biological Activity

Description ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM); a useful chemical tool to examine the functional role of this enzyme in skeletal mineralization and soft tissue ossification abnormalities.
References References 1. Stonich D, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. 2. Bravo Y, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4308-11. View Related Products by Target Protein Phosphatase/PTP

 Chemical & Physical Properties

Molecular Formula C16H14N2O2S
Molecular Weight 298.36
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