![]() ML 086 (CID-1674999) structure
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Common Name | ML 086 (CID-1674999) | ||
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CAS Number | 1177148-36-5 | Molecular Weight | 298.36 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C16H14N2O2S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of ML 086 (CID-1674999)ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM); a useful chemical tool to examine the functional role of this enzyme in skeletal mineralization and soft tissue ossification abnormalities. |
Name | ML 086 |
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Description | ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM); a useful chemical tool to examine the functional role of this enzyme in skeletal mineralization and soft tissue ossification abnormalities. |
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References | References 1. Stonich D, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. 2. Bravo Y, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4308-11. View Related Products by Target Protein Phosphatase/PTP |
Molecular Formula | C16H14N2O2S |
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Molecular Weight | 298.36 |