Name | APA modulator T5 |
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Description | APA modulator T5 is a small modulator of alternative polyadenylation (APA), modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts; predominantly induced CR-APA and UTR-APA; APA modulator T4 exhibits high potency and selectivity for APA modulation, inducing a preference for the use of proximal intronic poly(A) CSs with long intron regions through the PABPN1 pathway; APA modulator T4 is a valuable tool for increasing the understanding of the molecular mechanisms of APA and splicing. |
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References | References 1. Araki S, et al. Cell Chem Biol. 2018 Sep 26. pii: S2451-9456(18)30301-5. View Related Products by Target Other Targets |
Molecular Formula | C21H19N3O |
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Molecular Weight | 329.403 |