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1253731-24-6

1253731-24-6 structure
1253731-24-6 structure
  • Name: (2S,3R)-Voruciclib
  • Chemical Name: (2S,3R)-Voruciclib
  • CAS Number: 1253731-24-6
  • Molecular Formula: C22H19ClF3NO5
  • Molecular Weight: 469.84
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
  • Create Date: 2020-01-24 07:37:51
  • Modify Date: 2024-01-31 11:02:06
  • (2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. (2S,3R)-Voruciclib is an orally active CDK inhibitor[1].

Name (2S,3R)-Voruciclib
Description (2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. (2S,3R)-Voruciclib is an orally active CDK inhibitor[1].
Related Catalog
Target

CDK[1]

In Vitro (2S,3R)-Voruciclib (Compound B, formula I) is used in combination with a compound capable of inhibiting EGFR kinase activity and Gemcitabine to treat pancreatic cancer[1].
References

[1]. Veena Agarwal, et al. A synergistic pharmaceutical combination for the treatment of pancreatic cancer. WO2012123889A1.

Molecular Formula C22H19ClF3NO5
Molecular Weight 469.84