2250323-50-1
2250323-50-1 structure
- Name: JWG-071
- Chemical Name: JWG-071
- CAS Number: 2250323-50-1
- Molecular Formula: C34H44N8O3
- Molecular Weight: 612.76
- Catalog: Signaling Pathways MAPK/ERK Pathway ERK
- Create Date: 2020-01-23 16:43:51
- Modify Date: 2024-01-15 11:45:24
-
JWG-071 is the first reported kinase-selective chemical probe for ERK5. JWG-071 improves ERK5 activity and BRD4 selectivity. JWG-071 will be a much-needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology[1].
| Name | JWG-071 |
|---|
| Description | JWG-071 is the first reported kinase-selective chemical probe for ERK5. JWG-071 improves ERK5 activity and BRD4 selectivity. JWG-071 will be a much-needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology[1]. |
|---|---|
| Related Catalog | |
| Target |
ERK5:88 nM (IC50) |
| In Vitro | JWG-071 inhibits ERK5 and LRRK2 with IC50 of 88 and 109 nM, respectively[1]. |
| References |
| Molecular Formula | C34H44N8O3 |
|---|---|
| Molecular Weight | 612.76 |