1895922-69-6

1895922-69-6 structure

Name: Aminooxy-PEG1-propargyl HCl
Chemical Name: Aminooxy-PEG1-propargyl
CAS Number: 1895922-69-6
Molecular Formula: C₅H₉NO₂
Molecular Weight: 115.13
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-08 22:58:49
Modify Date: 2024-01-09 15:22:12
Aminooxy-PEG1-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	Aminooxy-PEG1-propargyl

Description	Aminooxy-PEG1-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.