1844894-82-1

1844894-82-1 structure
1844894-82-1 structure
  • Name: t-Boc-Aminooxy-PEG1-amine
  • Chemical Name: Boc-Aminooxy-PEG1-C2-NH2
  • CAS Number: 1844894-82-1
  • Molecular Formula: C9H20N2O4
  • Molecular Weight: 220.27
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:40:04
  • Modify Date: 2024-01-14 08:45:01
  • Boc-Aminooxy-PEG1-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-Aminooxy-PEG1-C2-NH2
Synonyms MFCD31561111
Description Boc-Aminooxy-PEG1-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C9H20N2O4
Molecular Weight 220.27
Hazard Codes Xi