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2055023-26-0

2055023-26-0 structure
2055023-26-0 structure
  • Name: Bis-PEG10-acid
  • Chemical Name: Bis-PEG10-acid
  • CAS Number: 2055023-26-0
  • Molecular Formula: C24H46O14
  • Molecular Weight: 558.61
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-12 12:49:31
  • Modify Date: 2024-01-10 10:41:18
  • Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name Bis-PEG10-acid
Description Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298.

Molecular Formula C24H46O14
Molecular Weight 558.61