2194563-83-0

2194563-83-0 structure
2194563-83-0 structure
  • Name: Hydroxy-PEG4-C2-nitrile
  • Chemical Name: Hydroxy-PEG4-C2-nitrile
  • CAS Number: 2194563-83-0
  • Molecular Formula: C11H21NO5
  • Molecular Weight: 247.29
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-05 11:44:17
  • Modify Date: 2024-01-02 16:16:04
  • Hydroxy-PEG4-C2-nitrile is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Hydroxy-PEG4-C2-nitrile
Description Hydroxy-PEG4-C2-nitrile is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C11H21NO5
Molecular Weight 247.29