1639933-78-0
1639933-78-0 structure
- Name: LolCDE-IN-1
- Chemical Name: LolCDE-IN-1
- CAS Number: 1639933-78-0
- Molecular Formula: C21H16FN3O
- Molecular Weight: 345.37
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2020-04-06 16:38:30
- Modify Date: 2024-01-17 20:02:49
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LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex, with antibacterial activity[1].
| Name | LolCDE-IN-1 |
|---|
| Description | LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex, with antibacterial activity[1]. |
|---|---|
| Related Catalog | |
| Target |
Bacterial |
| In Vitro | LolCDE-IN-1 (compound 2) inhibits the function of the LolCDE complex, which is required for transport of lipoproteins to the outer membrane[1]. LolCDE-IN-1 inhibits E. coli ATCC 25922 and E. coli ATCC 25922 ΔtolCwith MIC with 8 μg/ml and 0.125 μg/ml[1]. LolCDE-IN-1 inhibits bacterial growth by targeting LolCDE to block lipoprotein transport to the outer membrane[1]. |
| References |
| Molecular Formula | C21H16FN3O |
|---|---|
| Molecular Weight | 345.37 |