1410101-89-1
1410101-89-1 structure
- Name: (R)-PS210
- Chemical Name: (R)-PS210
- CAS Number: 1410101-89-1
- Molecular Formula: C19H15F3O5
- Molecular Weight: 380.31
- Catalog: Signaling Pathways PI3K/Akt/mTOR PDK-1
- Create Date: 2020-04-11 20:21:00
- Modify Date: 2024-01-15 18:15:11
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(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment[1].
| Name | (R)-PS210 |
|---|
| Description | (R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment[1]. |
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| Related Catalog | |
| Target |
AC50: 1.8 μM (PDK1)[1] |
| In Vitro | (R)-PS210 displays an AC50 value of 1.8 μM towards PDK1 in a Cell-Free Kinase Activity Assay. And the maximum activation of PDK1 compared to DMSO control of (R)-PS210 is 5.5 fold[1]. |
| References |
| Molecular Formula | C19H15F3O5 |
|---|---|
| Molecular Weight | 380.31 |