934985-98-5

934985-98-5 structure
934985-98-5 structure
  • Name: (10-BRomodecyl)phosphonic acid
  • Chemical Name: (10-BRomodecyl)phosphonic acid
  • CAS Number: 934985-98-5
  • Molecular Formula: C10H22BrO3P
  • Molecular Weight: 301.16
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:13:00
  • Modify Date: 2024-01-16 19:20:02
  • (10-BRomodecyl)phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name (10-BRomodecyl)phosphonic acid
Synonyms MFCD25424105
Description (10-BRomodecyl)phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H22BrO3P
Molecular Weight 301.16