2170240-99-8

2170240-99-8 structure
2170240-99-8 structure
  • Name: (2-pyridyldithio)-PEG4-propargyl
  • Chemical Name: (2-Pyridyldithio)-PEG4-propargyl
  • CAS Number: 2170240-99-8
  • Molecular Formula: C16H23NO4S2
  • Molecular Weight: 357.49
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:38:08
  • Modify Date: 2024-01-03 12:02:31
  • (2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name (2-Pyridyldithio)-PEG4-propargyl
Description (2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H23NO4S2
Molecular Weight 357.49