1428661-67-9

1428661-67-9 structure
1428661-67-9 structure
  • Name: Amino-Tri-(m-PEG4-ethoxymethyl)-methane
  • Chemical Name: Amino-Tri-(m-PEG4-ethoxymethyl)-methane
  • CAS Number: 1428661-67-9
  • Molecular Formula: C40H80N4O18
  • Molecular Weight: 905.08
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:33:12
  • Modify Date: 2024-01-23 12:46:50
  • Amino-Tri-(m-PEG4-ethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Amino-Tri-(m-PEG4-ethoxymethyl)-methane
Description Amino-Tri-(m-PEG4-ethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C40H80N4O18
Molecular Weight 905.08