2243566-43-8

2243566-43-8 structure
2243566-43-8 structure
  • Name: Azido-PEG3-amide-C3-triethoxysilane
  • Chemical Name: Azido-PEG3-amide-C3-triethoxysilane
  • CAS Number: 2243566-43-8
  • Molecular Formula: C18H38N4O7Si
  • Molecular Weight: 450.60
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:24:33
  • Modify Date: 2024-01-23 18:10:42
  • Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azido-PEG3-amide-C3-triethoxysilane
Description Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C18H38N4O7Si
Molecular Weight 450.60