525583-49-7

525583-49-7 structure
525583-49-7 structure
  • Name: Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine
  • Chemical Name: Boc-Gly-amido-C-PEG3-C3-amine
  • CAS Number: 525583-49-7
  • Molecular Formula: C17H35N3O6
  • Molecular Weight: 377.48
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 16:26:23
  • Modify Date: 2024-01-09 20:27:00
  • Boc-Gly-amido-C-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-Gly-amido-C-PEG3-C3-amine
Synonyms MFCD31380402
Description Boc-Gly-amido-C-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C17H35N3O6
Molecular Weight 377.48