Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine

Modify Date: 2024-01-09 20:27:00

Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine Structure
Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine structure
Common Name Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine
CAS Number 525583-49-7 Molecular Weight 377.48
Density N/A Boiling Point N/A
Molecular Formula C17H35N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine


Boc-Gly-amido-C-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Gly-amido-C-PEG3-C3-amine
Synonym More Synonyms

 Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine Biological Activity

Description Boc-Gly-amido-C-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H35N3O6
Molecular Weight 377.48

 Synonyms

MFCD31380402
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