Boc-Gly-PEG3-endo-BCN structure
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Common Name | Boc-Gly-PEG3-endo-BCN | ||
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CAS Number | 2110444-63-6 | Molecular Weight | 553.69 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C28H47N3O8 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Boc-Gly-PEG3-endo-BCNBoc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. |
Name | Boc-gly-PEG3-endo-BCN |
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Description | Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. |
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Related Catalog | |
Target |
PEGs Alkyl/ether Cleavable |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2]. |
References |
Molecular Formula | C28H47N3O8 |
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Molecular Weight | 553.69 |
Hazard Codes | Xi |
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