2055041-16-0

2055041-16-0 structure
2055041-16-0 structure
  • Name: Bromoacetamido-PEG8-t-butyl ester
  • Chemical Name: Bromoacetamido-PEG8-Boc
  • CAS Number: 2055041-16-0
  • Molecular Formula: C25H48BrNO11
  • Molecular Weight: 618.55
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:57:29
  • Modify Date: 2024-01-10 12:25:16
  • Bromoacetamido-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromoacetamido-PEG8-Boc
Synonyms MFCD29918248
Description Bromoacetamido-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H48BrNO11
Molecular Weight 618.55