Shanghai Nianxing Industrial Co., Ltd
China
Product Name: DBCO-PEG1-NHS ester
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

2228857-34-7

2228857-34-7 structure

2228857-34-7 structure

Name: DBCO-PEG1-NHS ester
Chemical Name: DBCO-PEG1-NHS ester
CAS Number: 2228857-34-7
Molecular Formula: C₂₈H₂₇N₃O₇
Molecular Weight: 517.53
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-05 10:03:16
Modify Date: 2024-01-12 14:16:17
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG1-NHS ester
Synonyms	MFCD31615436

Description	DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₈H₂₇N₃O₇
Molecular Weight	517.53