2112737-93-4

2112737-93-4 structure
2112737-93-4 structure
  • Name: DSPE-PEG5-propargyl
  • Chemical Name: DSPE-PEG5-propargyl
  • CAS Number: 2112737-93-4
  • Molecular Formula: C55H104NO14P
  • Molecular Weight: 1034.39
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:19:11
  • Modify Date: 2024-01-17 18:42:03
  • DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DSPE-PEG5-propargyl
Description DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C55H104NO14P
Molecular Weight 1034.39