169327-87-1

169327-87-1 structure

169327-87-1 structure

Name: Fluazinam impurity 1
Chemical Name: Fluazinam impurity 1
CAS Number: 169327-87-1
Molecular Formula: C₁₃H₄Cl₂F₆N₄O₄
Molecular Weight: 465.09
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2020-06-01 17:40:43
Modify Date: 2024-01-11 17:05:30
Fluazinam impurity 1 is an impurity of Fluazinam with antifungal activity. Fluazinam impurity 1 is active against Sphaerotheca fuliginea, Pyricularia oryzae and Rhizoctonia solani[1].

Name	Fluazinam impurity 1

Description	Fluazinam impurity 1 is an impurity of Fluazinam with antifungal activity. Fluazinam impurity 1 is active against Sphaerotheca fuliginea, Pyricularia oryzae and Rhizoctonia solani[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
Target	Fungal[1]
In Vitro	Quantitative structure-activity relationships (QSAR) analyses of fungicidal activity of Fluazinam impurity 1 against Sphaerotheca fuliginea, Pyricularia oryzae and Rhizoctonia solani are carried out and the results are compared. In the case of S. fuliginea, a usual QSAR equation with Hammett's electronic parameter (sigma-m) and hydrophobicity (pi) is obtained, suggesting that the uncoupling mechanism might be involved in the mode of action. In the cases of P. oryzae and R. solani, QSAR equations are consisted of sigma-m, pi and the activity rank against Botrytis cinerea as independent variables,indicating both of uncoupling and SH-inhibition are working in the action mechanism[1].
References	[1]. Toshio Akagi, et al. Quantitative structure-activity relationships of fluazinam and related fungicidal N-phenylpyridinamines : preventive activity against Botrytis cinerea. Nippon Noyaku Gakkaishi (1995), 20(3), 279-90.

Molecular Formula	C₁₃H₄Cl₂F₆N₄O₄
Molecular Weight	465.09