2243942-52-9

2243942-52-9 structure
2243942-52-9 structure
  • Name: HO-PEG24-OH
  • Chemical Name: HO-PEG24-OH
  • CAS Number: 2243942-52-9
  • Molecular Formula: C48H98O25
  • Molecular Weight: 1075.28
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:30:00
  • Modify Date: 2024-01-11 18:46:30
  • HO-PEG24-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name HO-PEG24-OH
Synonyms MFCD28976705
Description HO-PEG24-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C48H98O25
Molecular Weight 1075.28