Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ho-peg8-ch2cooh
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

780006-30-6

780006-30-6 structure

780006-30-6 structure

Name: HO-PEG8-CH2COOH
Chemical Name: HO-PEG8-CH2COOH
CAS Number: 780006-30-6
Molecular Formula: C₁₈H₃₆O₁₁
Molecular Weight: 428.47
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 21:14:13
Modify Date: 2024-01-09 13:02:31
HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	HO-PEG8-CH2COOH

Description	HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₈H₃₆O₁₁
Molecular Weight	428.47