2207596-93-6

2207596-93-6 structure
2207596-93-6 structure
  • Name: m-PEG12-NHS ester
  • Chemical Name: m-PEG12-NHS ester
  • CAS Number: 2207596-93-6
  • Molecular Formula: C30H55NO16
  • Molecular Weight: 685.75
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:40:26
  • Modify Date: 2024-01-08 18:22:28
  • m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG12-NHS ester
Description m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C30H55NO16
Molecular Weight 685.75