2353410-18-9

2353410-18-9 structure

2353410-18-9 structure

Name: Methyltetrazine-PEG24-amine
Chemical Name: Methyltetrazine-PEG24-amine
CAS Number: 2353410-18-9
Molecular Formula: C₅₇H₁₀₅N₅O₂₄
Molecular Weight: 1244.50
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 09:28:26
Modify Date: 2024-01-20 11:02:26
Methyltetrazine-PEG24-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyltetrazine-PEG24-amine

Description	Methyltetrazine-PEG24-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₅₇H₁₀₅N₅O₂₄
Molecular Weight	1244.50