2183440-72-2

2183440-72-2 structure
2183440-72-2 structure
  • Name: N-(Azido-PEG3)-NH-PEG3-acid HCl
  • Chemical Name: N-(Azido-PEG3)-NH-PEG3-acid
  • CAS Number: 2183440-72-2
  • Molecular Formula: C17H34N4O8
  • Molecular Weight: 422.47
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:14:59
  • Modify Date: 2024-01-09 18:18:30
  • N-(Azido-PEG3)-NH-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Azido-PEG3)-NH-PEG3-acid
Description N-(Azido-PEG3)-NH-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C17H34N4O8
Molecular Weight 422.47