2100306-63-4

2100306-63-4 structure
2100306-63-4 structure
  • Name: N-(Boc-PEG1)-N-bis(PEG2-propargyl)
  • Chemical Name: N-(Boc-PEG1)-N-bis(PEG2-propargyl)
  • CAS Number: 2100306-63-4
  • Molecular Formula: C23H40N2O7
  • Molecular Weight: 456.57
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:48:27
  • Modify Date: 2024-01-16 21:07:25
  • N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Boc-PEG1)-N-bis(PEG2-propargyl)
Synonyms MFCD30723238
Description N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C23H40N2O7
Molecular Weight 456.57
Hazard Codes Xi