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1835759-84-6

1835759-84-6 structure
1835759-84-6 structure
  • Name: N-Me-N-bis(PEG2-propargyl)
  • Chemical Name: N-Me-N-bis(PEG2-propargyl)
  • CAS Number: 1835759-84-6
  • Molecular Formula: C15H25NO4
  • Molecular Weight: 283.36
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:28:36
  • Modify Date: 2024-01-11 06:05:04
  • N-Me-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-Me-N-bis(PEG2-propargyl)
Synonyms MFCD29042338
Description N-Me-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H25NO4
Molecular Weight 283.36