2100306-85-0

2100306-85-0 structure
2100306-85-0 structure
  • Name: N-(PEG1-OH)-N-Boc-PEG2-propargyl
  • Chemical Name: N-(PEG1-OH)-N-Boc-PEG2-propargyl
  • CAS Number: 2100306-85-0
  • Molecular Formula: C16H29NO6
  • Molecular Weight: 331.40
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:13:09
  • Modify Date: 2024-01-10 10:28:05
  • N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(PEG1-OH)-N-Boc-PEG2-propargyl
Synonyms MFCD30730381
Description N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H29NO6
Molecular Weight 331.40