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1814901-04-6

1814901-04-6 structure
1814901-04-6 structure
  • Name: NH-(PEG3-acid)2
  • Chemical Name: NH-bis(PEG3-acid)
  • CAS Number: 1814901-04-6
  • Molecular Formula: C18H35NO10
  • Molecular Weight: 425.47
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:00:39
  • Modify Date: 2024-01-12 12:25:49
  • NH-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH-bis(PEG3-acid)
Synonyms MFCD29912752
Description NH-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C18H35NO10
Molecular Weight 425.47