2179113-08-5

2179113-08-5 structure
2179113-08-5 structure
  • Name: PEG20-Tos
  • Chemical Name: PEG20-Tos
  • CAS Number: 2179113-08-5
  • Molecular Formula: C47H88O23S
  • Molecular Weight: 1053.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:19:24
  • Modify Date: 2024-01-22 11:38:57
  • PEG20-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name PEG20-Tos
Synonyms MFCD29079389
Description PEG20-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C47H88O23S
Molecular Weight 1053.25